Rampage is a 2018 American science fiction monster film directed by Darren Lynn Bousman and written by Jean-Benoît Levis and Patrick Wilson. The movie is based on the popular arcade game of the same name. The film stars Dwayne Johnson, Joseph Lee Anderson, and Jack Huston.

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During an experiment, David's friend and colleague, Dr. Claire Wilson (Naomie Harris), tries to cure a genetic disorder in George and his fellow animals, which include an alligator named Ralph and a wolf named Lyle. However, the experiment goes awry, and the animals are exposed to a gene that enhances their size, aggression, and intelligence.